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Maintenance of Laboratory Animals as per CPCSEA Guidelines

All establishments engaged in research and education involving animals in India are required to comply with the various guidelines, norms and stipulations set out by CPCSEA. The aim of these guidelines is to ensure humane and ethical treatment of animals, while facilitating legitimate scientific research involving experiments on animals and to make judicious use of animals for experimental purposes. Committee for Purpose of Control andSupervision of Experiments on Animals (CPCSEA): The Prevention of Cruelty to Animals Act 1960 as amended in 1982, is to prevent the unnecessary pain or suffering on animals. The Central Government has constituted a Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA) which ensures that animals are not subjected to unnecessary pain or suffering before, during or after the performance of experiments on them. For this purpose, the Government has made "Breeding of and Experiments on Animals (Control and Superv

Commonly Used Experimental Animals In Pharmacology Laboratory

Laboratory animals are those animals which can be bred and maintained in the laboratory under suitable conditions by the taking permission of regulatory authorities. Guinea pig has become synonymous to the experimental animals, but many other species are equally useful in the study of drugs. Pre clinical studies of experimental pharmacology involve laboratory animals using wide ‐ ranging doses of the study drug to obtain preliminary efficacy, toxicity and pharmacokinetic information. Such tests assist pharmaceutical companies to decide whether a drug candidate has scientific merit for further development as an investigational new drug. Preclinical study involves the use of laboratory animals. Experimental animals can be classified as: 1.      Rodents - Rat, Mouse, Guinea pig, Hamster etc. 2.      Non rodents - Rabbit, Dog, Cat, Pig, Monkey etc. 3.      Miscellaneous - Frog, Pigeon, chicken etc. The commonly used laboratory animals in pharmacology laboratory are Frog, Rat, Mi