The aims of experimental pharmacology are discovery and development of the new drugs, study of the mechanism and site of action of different drugs and study the toxicity effect of a drug. Experimental pharmacology consists of preclinical study and clinical study . Figure 1: Types of experimental Pharmacology Preclinical pharmacology Preclinical studies involve in-vivo and in-vitro experiments using wide range of doses of the sample drug to obtain preliminary efficacy, toxicity and pharmacokinetic information. Such tests assist pharmaceutical companies to decide whether a drug candidate has scientific merit for further development as an investigational new drug (IND). In-vivo (animal testing) study is used to measure: how much of a drug is absorbed into the blood, how it is broken down chemically in the body, the toxicity of the drug and its breakdown products or metabolites, and how quickly the drug and its metabolites are excreted from the body. Short-term test
A distinct way of learning experimental pharmacology....